搜索



赛默飞世尔科技为您服务
联系销售
联系技术与支持
相关产品列表
产品类别- 质谱 >>LC/MS >>LC/MS 附件 >>
点击放大
液相色谱(LC) IsoLink联机接口
On-line coupling of HPLC and Isotope Ratio MS
  • Isotope ratio data on an HPLC time scale
  • Integrity of chromatographic resolution
  • High sensitivity sample analysis in the low nano-mol range
  • Accurate and reproducible results
  • Direct injection of international reference materials
  • Maintenance-free operation
  • High throughput
  • Full automation capability
The LC IsoLink is the first high sensitivity interface connecting HPLC with Isotope Ratio MS for the reproducible and accurate on-line determination of 13C/12C isotope ratios. All organic compounds eluting from an HPLC column are analyzed while maintaining the chromatographic resolution. This opens up a whole new world in the application of isotope ratio mass spectrometry.

The LC IsoLink is built to directly address the analysis of polar and thermo-labile compounds.Most of these compounds (such as amino acids, peptides, carbohydrates, nucleotides, alcohols, organic acids, sulfa drugs, and many more) can be chromatographically separated in aqueous phase using inorganic buffers on ion exchange, size exclusion or specific reversed phase HPLC columns.The LC IsoLink enables the on-line high precision determination of the 13C/12C isotope ratio of each separated component.

Metabolism studies

  • Tracer experiments with amino acids, lipids, carbohydrates
  • Nucleotide analysis for DNA synthesis rates

Food and food ingredients

  • Adulteration control of honey and fruit juices
  • Determination of origin of flavors and nutrients
  • Analysis of phospholipids, carbohydrates, amino acids and vitamins

Pharmaceuticals

  • Authenticity control of drugs
  • Investigation of agents and additives

Doping control

  • Analysis of steroids and hormones

Biogeochemistry

  • History of biomolecules in sediments and soils

Click here for Trainings information